Florida-based Biotech Company Develops Water-soluble Nano CBD Ingredient With 30% Concentration to Enhance Formulation Efficacy

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This article was sponsored by Planta Scientific, a Florida-based biotechnology company that formulates and manufactures patented nano cannabinoid ingredients for consumer products.

Planta Scientific’s recent nano cannabidiol (CBD) skin penetration study using their patented nano E-200 CBD ingredient demonstrated dramatically improved CBD absorption rates. The results of the ex-vivo human skin tissue study found that the E-200 delivery system significantly improved the skin penetration of CBD, delivering four times more CBD through the skin at 3.3 times deeper layers of the dermis than traditional CBD.  

Cannabidiol, the non-psychoactive phytocannabinoid found in cannabis plants, has emerged as a potential therapeutic ingredient for use in consumer goods such as ingestibles (gummies, candy, chocolate), topicals (skincare, makeup), transdermal patches, beverages, and therapeutics (tinctures, gel caps). However, CBD as a raw material is a large molecule and highly lipophilic. The large molecule size and its low solubility in water create challenges not only for formulators and manufacturers but also for deliverability and overall consumer experience.

To maximize CBD’s potential benefits, efficacy, and ease of use, Miami-based biotechnology company Planta Scientific developed E-200 CBD, a high-concentration, water-soluble nano CBD ingredient designed for easy incorporation into formulations such as lotions, serums, edibles, beverages, transdermal patches, and other consumer products.

This water-soluble cannabidiol absorbs into the human body more readily than oil-based CBD. Users of water-soluble topical CBD products can benefit from the compound’s health and wellness properties.

“Planta’s water-soluble E-200 CBD provides a 30% concentration of CBD with a lipid particle size of 200nm for rapid absorption into the skin,” says Mario Tremblay, Ph.D., chief science officer at Planta Scientific. “It also penetrates deeper than other CBD and CBD emulsion products, allowing users to see more efficient, targeted results. The Planta E-200 CBD offers formulators maximum flexibility, as it is ideal for a wide range of product formulations. You just drop it in — no extra startup costs or specialized equipment necessary.”

The THC-free CBD’s nano size and lipid encapsulation technology stabilize the CBD in formulations and help extend product life. Planta Scientific uses 100% U.S.-grown hemp feedstock to extract the CBD found in E-200 CBD. CBD is naturally oily and does not dissolve readily in water, so Planta Scientific uses nanotechnology techniques to break down and encapsulate the CBD into nano-sized particles, increasing the CBD’s surface area and solubility in water while improving its bioavailability.

Planta Scientific offers 25 mL samples of E-200 CBD to qualified businesses and formulation support for CBD product developers.

Request your sample or learn more about the Planta E-200 CBD here.

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